Study finds social isolation increases depression risk in cancer patients

Recent research highlights the impact of social isolation on depression among colorectal cancer (CRC) patients who have undergone colostomy procedures. This cross-sectional study examined 290 patients treated between January 2020 and January 2023, revealing that 139 of them were diagnosed with depression.

Colorectal cancer poses significant physical and psychological challenges. Many patients undergo colostomy, which can alter their daily lives and increase vulnerability to mental health issues. The study specifically focused on the relationship between social isolation and depressive symptoms in these patients, an area that has not been thoroughly explored.

To assess mental health, researchers utilized the Chinese version of the Patient Health Questionnaire (PHQ-9), which evaluates the severity of depression. They also measured social isolation using the Lubben Social Network Scale (LSNS-6). Additional data collected included demographic details, clinical conditions, psychosocial adjustments, and levels of social support.

Findings indicated that patients in advanced tumor stages (III-IV) had nearly double the odds of experiencing depression (Odds Ratio [OR] = 1.94) compared to those in earlier stages. Furthermore, a longer duration of colostomy significantly increased the risk, with an OR of 4.04. In contrast, social isolation emerged as a protective factor, with an OR of 0.24, suggesting that individuals with stronger social connections tended to experience fewer depressive symptoms.

The prevalence of depression was notably higher in socially isolated patients, with 58.8% showing depressive symptoms compared to 43.8% in those with stronger social networks. Subgroup analyses indicated that the negative effects of social isolation were more pronounced in males, patients aged 70 and older, and those who were divorced, widowed, or single. Individuals with low social support also exhibited stronger associations with depression.

These findings underscore the need for healthcare providers to evaluate patients’ social environments and the extent of their social isolation, particularly following colostomy procedures. Implementing targeted interventions to foster social connections could play a vital role in reducing depression rates among colorectal cancer patients. By prioritizing social support and community engagement, healthcare systems can improve the mental health outcomes of this vulnerable population.